Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2013 2
2014 1
2015 1
2016 1
2020 2
2021 1
2022 1
2023 1
2024 0

Text availability

Article attribute

Article type

Publication date

Search Results

9 results

Results by year

Filters applied: . Clear all
Page 1
Inhibition of protein phosphatase methylesterase 1 dysregulates MAP kinase signaling and attenuates muscle cell differentiation.
Labuzan SA, Lynch SA, Cooper LM, Waddell DS. Labuzan SA, et al. Gene. 2020 May 20;739:144515. doi: 10.1016/j.gene.2020.144515. Epub 2020 Feb 26. Gene. 2020. PMID: 32112987
Protein phosphatase methylesterase 1 has been identified as a novel gene in skeletal muscle that is upregulated in response to neurogenic atrophy in mice. ...Additionally, the Ppme1 promoter is active in muscle cells, while mutation of a conserv …
Protein phosphatase methylesterase 1 has been identified as a novel gene in skeletal muscle that is upregulated …
Protein phosphatase methylesterase-1 (PME-1) expression predicts a favorable clinical outcome in colorectal cancer.
Kaur A, Elzagheid A, Birkman EM, Avoranta T, Kytölä V, Korkeila E, Syrjänen K, Westermarck J, Sundström J. Kaur A, et al. Cancer Med. 2015 Dec;4(12):1798-808. doi: 10.1002/cam4.541. Epub 2015 Sep 17. Cancer Med. 2015. PMID: 26377365 Free PMC article.
Analysis of PPME-1 mRNA expression from TCGA dataset of colon and rectal adenocarcinoma (COADREAD) patient cohort confirmed high PPME1 expression as an independent protective factor predicting favorable overall survival (OS) (P = 0.005, n = 396) compared to patients with l …
Analysis of PPME-1 mRNA expression from TCGA dataset of colon and rectal adenocarcinoma (COADREAD) patient cohort confirmed high PPME1 …
PP2A methylesterase PME-1 suppresses anoikis and is associated with therapy relapse of PTEN-deficient prostate cancers.
Aakula A, Isomursu A, Rupp C, Erickson A, Gupta N, Kauko O, Shah P, Padzik A, Pokharel YR, Kaur A, Li SP, Trotman L, Taimen P, Rannikko A, Lammerding J, Paatero I, Mirtti T, Ivaska J, Westermarck J. Aakula A, et al. Mol Oncol. 2023 Jun;17(6):1007-1023. doi: 10.1002/1878-0261.13353. Epub 2023 Apr 18. Mol Oncol. 2023. PMID: 36461911 Free PMC article.
Knockdown of microRNA-195 contributes to protein phosphatase-2A inactivation in rats with chronic brain hypoperfusion.
Liu CD, Wang Q, Zong DK, Pei SC, Yan Y, Yan ML, Sun LL, Hao YY, Mao M, Xing WJ, Ren H, Ai J. Liu CD, et al. Neurobiol Aging. 2016 Sep;45:76-87. doi: 10.1016/j.neurobiolaging.2016.05.010. Epub 2016 May 18. Neurobiol Aging. 2016. PMID: 27459928
In vitro studies demonstrated that miR-195 regulated PME-1 expression by binding to the Ppme1 gene 3'-untranslated region (3'UTR) domain. Masking the miR-195 binding sites in the amyloid precursor protein (APP) and beta-site APP cleaving enzyme 1 genes prevented miR-195-in …
In vitro studies demonstrated that miR-195 regulated PME-1 expression by binding to the Ppme1 gene 3'-untranslated region (3'UTR) dom …
Hsa_circ_0050102 regulates the pancreatic cancer development via miR-218-5p/PPME1 axis.
Feng N, Jiao Z, Zhang Y, Yang B. Feng N, et al. J Clin Lab Anal. 2022 Mar;36(3):e24247. doi: 10.1002/jcla.24247. Epub 2022 Jan 21. J Clin Lab Anal. 2022. PMID: 35060203 Free PMC article.
METHODS: Hsa_circ_0050102, microRNA-218-5p (miR-218-5p) and protein phosphatase methylesterase 1 (PPME1) abundances were indicated by quantitative RT-PCR or Western blot. ...Furthermore, miR-218-5p was established to block the development of PC …
METHODS: Hsa_circ_0050102, microRNA-218-5p (miR-218-5p) and protein phosphatase methylesterase 1 (PPME1) …
Genetic amplification of PPME1 in gastric and lung cancer and its potential as a novel therapeutic target.
Li J, Han S, Qian Z, Su X, Fan S, Fu J, Liu Y, Yin X, Gao Z, Zhang J, Yu DH, Ji Q. Li J, et al. Cancer Biol Ther. 2014 Jan;15(1):128-34. doi: 10.4161/cbt.27146. Epub 2013 Nov 19. Cancer Biol Ther. 2014. PMID: 24253382 Free PMC article.
Protein phosphatase methylesterase 1 (PPME1) is a protein phosphatase 2A (PP2A)-specific methyl esterase that negatively regulates PP2A through demethylation at its carboxy terminal leucine 309 residue. ...Our data indicate that PPME1 cou …
Protein phosphatase methylesterase 1 (PPME1) is a protein phosphatase 2A (PP2A)-specific methyl esterase …
Long non-coding RNA HOTAIR/microRNA-761 sponge regulates PPME1 and further influences cell biological functions in thyroid carcinoma.
Guo R, Ning Y, Ma Y, Lin Q, Shen N, Shi P. Guo R, et al. Laryngoscope Investig Otolaryngol. 2021 May 26;6(3):438-445. doi: 10.1002/lio2.593. eCollection 2021 Jun. Laryngoscope Investig Otolaryngol. 2021. PMID: 34195365 Free PMC article.
AIM OF THE STUDY: To explore the role of homeobox transcript antisense RNA (HOTAIR) in thyroid carcinoma through protein phosphatase methylesterase 1 (PPME1) by sponging microRNA 761 (miR-761). ...CONCLUSION: HOTAIR regulated thyroid cancer cell …
AIM OF THE STUDY: To explore the role of homeobox transcript antisense RNA (HOTAIR) in thyroid carcinoma through protein phosphata …
IMP1 promotes choriocarcinoma cell migration and invasion through the novel effectors RSK2 and PPME1.
Hsieh YT, Chou MM, Chen HC, Tseng JJ. Hsieh YT, et al. Gynecol Oncol. 2013 Oct;131(1):182-90. doi: 10.1016/j.ygyno.2013.07.106. Epub 2013 Aug 1. Gynecol Oncol. 2013. PMID: 23911878
Microarray and RNA-immunoprecipitation results revealed several candidate genes regulated by IMP1. Among them, ribosomal protein S6 kinase (RSK2) and protein phosphatase methylesterase 1 (PPME1) were confirmed to be down-regulated in IMP1-deplet …
Microarray and RNA-immunoprecipitation results revealed several candidate genes regulated by IMP1. Among them, ribosomal protein S6 kinase ( …
DNAH17-AS1 promotes pancreatic carcinoma by increasing PPME1 expression via inhibition of miR-432-5p.
Xu T, Lei T, Li SQ, Mai EH, Ding FH, Niu B. Xu T, et al. World J Gastroenterol. 2020 Apr 21;26(15):1745-1757. doi: 10.3748/wjg.v26.i15.1745. World J Gastroenterol. 2020. PMID: 32351291 Free PMC article.
In addition, the regulatory effects of DNAH17-AS1 on miR-432-5p, PPME1, and tumor activity were investigated using luciferase reporter assay, MTT viability analysis, flow cytometry, and transwell migration analysis. ...In addition, DNAH17-AS1 served as a PC oncogene by dow …
In addition, the regulatory effects of DNAH17-AS1 on miR-432-5p, PPME1, and tumor activity were investigated using luciferase reporte …